Metafolin® is already in the active form used by the body1
Absorbing Iron
Includes a chelated form of iron more readily absorbed in the small intestine, farther away from the gastric acidity of the duodenum. The absorption of iron is aided by ascorbic acid, "pushing" iron through the cell membrane of the small intestine.2
Safety Information
This product has a black box warning because of potential iron therapy overload. Acute iron poisoning is rare in adults but can be fatal in children under 6 who take adult-strength tablets. Some patients on iron therapy may experience constipation, diarrhea, and abdominal pain, but these symptoms are usually transient. They are rarely severe, although iron tablets can aggravate existing gastrointestinal problems. Some people have reported allergic reactions to folic acid. Nausea and vomiting may occur with high doses, but can be controlled by taking smaller amounts. Black stools are common when taking iron tablets. This product should not be used for people who suffer from hemochromatosis or hemosiderosis.
Willems FF, Boers GH, Blom HJ, et al. Pharmacokinetic Study on the Utilization of 5-methyltetrahydrofolate and Folic Acid in Patients with Coronary Artery disease. Br. J Pharmacol 2004;141:825-830.
Jeppsen RB, Toxicology and safety of ferrochel and other amino acid chelates, Arch Latinoam Nutr. 2001;51 (1 suppl 1):26-34.
